Post-transcriptional regulation by NANOS is up-regulated and functionally significant in pRb deficient cells

Thank you again for submitting your manuscript to The EMBO Journal. I need to apologize for the undue delay in getting back to you with a decision, which was owed to one of the referees unfortunately being very late in sending their report. We have now finally received all three sets of comments, copied below for your information. As you will see, the referees express (to varying degrees) interest in your findings and conclusion, but also raise a number of major issues that would need to be satifactorily clarified and improved before eventual publication.